August 28th, 2018

Leif Gram: Mr. Fix

Успехи борьбы с курением

Nature/Neuroscisence -- Cannabis use is a heritable trait that has been associated with adverse mental health outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to date (N =  184,765), we identified eight genome-wide significant independent single nucleotide polymorphisms in six regions. All measured genetic variants combined explained 11% of the variance. Gene-based tests revealed 35 significant genes in 16 regions, and S-PrediXcan analyses showed that 21 genes had different expression levels for cannabis users versus nonusers. The strongest finding across the different analyses was CADM2, which has been associated with substance use and risk-taking. Significant genetic correlations were found with 14 of 25 tested substance use and mental health–related traits, including smoking, alcohol use, schizophrenia and risk-taking. Похоже, будут бороться с риск-тейкингом. Хедж-фондам и страховым компаниям приготовиться.

Бонус: Талмуд запрещает освобождать рабов без их согласия.